Monkeypox Symptoms and Everything you need to know

Monkeypox is a viral infection caused by the monkeypox virus that can cause discomforting symptoms like fever, swollen lymph nodes, and a painful rash. Although most people who contract the virus will recover, some can experience severe illness.

Monkeypox is highly contagious and can be spread through contact with infected individuals, animals, or contaminated materials, including sheets, clothes, and needles. Even pregnant women can transmit the virus to their unborn babies. If you develop monkeypox, it’s important to let anyone who has been in close contact with you know about your diagnosis and to stay at home until all scabs fall off and new skin forms.

Covering lesions and wearing a mask when around others is also recommended. The monkeypox virus, which belongs to the Poxviridae family, was first discovered in monkeys in Denmark in 1958 and the first human case was reported in the Democratic Republic of the Congo in 1970. The virus can be transmitted from person to person or from animals to humans, and it is suspected to have originated in small mammals such as monkeys and squirrels, although its natural reservoir remains unknown. Despite the eradication of smallpox in 1980, monkeypox has continued to emerge in central, east, and west Africa, with a global outbreak occurring between 2022 and 2023. The virus is categorized into two genetic clades, clades I and II.


Mpox is a highly contagious disease caused by the monkeypox virus. The virus can spread from person to person through direct contact with infectious skin or lesions, including skin-to-skin contact, mouth-to-mouth contact, or through respiratory droplets or short-range aerosols from prolonged close contact. It can also be transmitted from animals to humans through bites, scratches, or during activities such as hunting, skinning, trapping, or cooking animals. The virus can even spread through contaminated objects such as clothing or linens. People with multiple sexual partners are at a higher risk of contracting the disease. It is important to note that the extent of viral circulation in animal populations is not entirely known, and further studies are currently underway to better understand this aspect of the disease

Monkeypox Symptoms

Mpox is a contagious viral disease that can cause a range of symptoms. These symptoms typically begin within a week of exposure and can last for 2-4 weeks, although they may persist longer in people with weakened immune systems. Common symptoms of mpox include fever, rash, sore throat, headache, muscle aches, back pain, low energy, and swollen lymph nodes. The rash usually starts as a flat sore and develops into a blister filled with liquid, which can be itchy or painful. The lesions then dry up, crust over, and fall off.

Mpox can be particularly serious for children, pregnant people, and those with weakened immune systems, who are at higher risk for complications. The disease can also cause a range of complications, including skin infections, pneumonia, vision loss, inflammation of various organs, and even death. People with immune suppression due to medication or medical conditions are at a higher risk of serious illness and death due to mpox.

The disease is highly infectious and can be transmitted until all sores have healed and a new layer of skin has formed. In the context of the global outbreak of mpox which began in 2022, the illness can begin differently in some people, with a rash appearing before or at the same time as other symptoms, and the first lesion appearing in the groin, anus, or in or around the mouth. It’s important to take precautions to avoid exposure to mpox and seek medical attention if you experience any symptoms.

Diagnosis after monkeypox symptoms appear

Identifying mpox can be a challenging task as the symptoms can resemble those of other infections and conditions. It is crucial to differentiate mpox from other diseases, including chickenpox, measles, bacterial skin infections, scabies, herpes, syphilis, and other sexually transmitted infections, as well as medication-associated allergies. Additionally, someone with mpox may also have another sexually transmitted infection such as herpes, while a child with suspected mpox may also have chickenpox. Therefore, testing is essential for prompt treatment and to prevent further spread of the disease.

PCR testing to detect viral DNA is the preferred laboratory test for mpox. The best samples for testing are taken directly from the rash, including skin, fluid, or crusts, which are collected through vigorous swabbing. If skin lesions are absent, testing can be performed on oropharyngeal, anal, or rectal swabs. However, testing blood is not recommended. It is important to note that antibody detection methods may not be useful as they do not distinguish between different orthopoxviruses.

Treatment and Vaccine after monkeypox symptoms appear

The primary objective when dealing with mpox is to manage the symptoms, take care of the rash, and prevent complications. Prompt and supportive care is crucial in order to alleviate symptoms and prevent complications.

Getting vaccinated against mpox can be an effective way to prevent infection. The vaccine should be administered within four days of contact with an infected person (or up to 14 days if no symptoms are present). During an outbreak, it is particularly important for individuals at high risk to receive the vaccine. These groups include healthcare workers at risk of exposure, men who have sex with men, people with multiple sex partners, and sex workers.

Individuals with mpox should be isolated from others to prevent the spread of the virus. Several antiviral medications, including tecovirimat, have been used to treat mpox, and further research is ongoing. Additional information on mpox vaccination and case management is also available.

Self-care and Prevention

The priority when dealing with mpox is to manage symptoms, prevent complications, and avoid infecting others. Recovery typically takes between 2-4 weeks, and there are steps that can be taken to ease symptoms and prevent the spreading of the virus.

To prevent infecting others, people with mpox should stay home and in their own rooms if possible. Frequent hand washing, wearing a mask and covering lesions when around others, keeping skin dry and uncovered, avoiding touching shared items, and disinfecting shared spaces are important measures to take.

For symptom management, people with mpox should avoid popping blisters or scratching sores, as this can slow healing, spread the rash to other parts of the body, and cause infections. They should also avoid shaving areas with sores until scabs have healed and new skin has formed. Over-the-counter pain medications like paracetamol (acetaminophen) or ibuprofen can be taken to manage pain.

To prevent the spread of mpox to others, people with the virus should isolate themselves at home or in a hospital if necessary, for the duration of the infectious period, which is from the onset of symptoms until lesions have healed and scabs have fallen off. Using condoms during sex can help reduce the risk of transmission, but they will not prevent skin-to-skin or mouth-to-skin contact from spreading the virus.

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